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fora historyczne
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Badania a dna

Post autor: fora historyczne » 15 paź 2012, 22:51

Najnowsze ustalenia genetyków na konferencji:

DNA in Forensics 2012, Sep 06-08 2012
5th International EMPOP Meeting 8th International Forensic Y-User Workshop

The history of slavs in the light of Y chromosome and mtDNA variability

Mielnik - Sikorska M1, Daca P2, Woźniak M1,*, Malyarchuk BA3, Derenko MV3, Skonieczna K1,4, Grzybowski T1
1Nicolaus Copernicus University, Ludwik Rydygier Collegium Medicum, Institute of Forensic Medicine, Department
of Molecular and Forensic Genetics, Bydgoszcz, Poland
2Institute of Human Genetics, Polish Academy of Sciences, Poznań, Poland
3Institute of Biological Problems of the North, Far-East Branch of the Russian Academy of Science, Magadan, Russia
4The Postgraduate School of Molecular Medicine, Medical University of Warsaw, Warsaw, Poland

To explore the origin of Eastern Europeans we investigated Y chromosome and mitochondrial H5
haplogroup diversity in population samples from Ukraine and other Eastern European countries. Y
chromosome diversity was analyzed using a panel of 11 SNP polymorphisms (including M458 – so
called “Western Slavic marker”) and 17 Y-STRs on 154 DNA samples from Ukrainians. These
results were compared to previously published data from Slavic and non-Slavic populations.
Mitochondrial DNA control-region sequences of about 2700 samples obtained from Eastern
(Russians and Ukrainians) and Western Slavs (Czechs, Poles and Slovaks) were used to select 51
samples representing mitochondrial H5 haplogroup. For these mtDNAs the entire genome
sequences were determined. Together with published data we have collected 210 complete mtDNA
sequences belonging to the H5 haplogroup. Thus, improvement of the resolution of H5 haplogroup
phylogeny and evolutionary age estimation of H5 subhaplogroups were possible. We were able to
identify a number of new subhaplogroups (i.e. H5a1a1, H5a1r, H5a1s and others) as well as to
show that the founder H5 clade (12-15 ky old) is mainly represented by individuals from southern
Europe. We also showed some subclusters (H5a1a, H5a1f, H5e1a, H5a2 and H5u), which are
mainly represented by residents of central and eastern Europe. The evolutionary age of these
subhaplogorups was dated between 2-5 ky. The overall picture of Y chromosome and mtDNA
diversity in Central Europe corresponds well with origin and later expansion of Corded Ware
European culture. Thus, we suggest that genetic continuity existed in Central Europe between
Bronze Age and Middle Ages when the earliest Slavic tribes were described.


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